Over a year has passed since the Uprising, and the Smoky Mountains are slowly healing from the zombie outbreak that threatened the entire world. Buford and Rue begin their new lives protecting their beloved home, while Buford balances his duties between being a park ranger and training a new generation of Red Tunic initiates. Buford and Dolly get married and set off on a turbulent honeymoon. Things are looking up for Rue as he settles into his new role as the Townsend chief of police, until an old enemy returns to settle a score with the Forrester clan.

Gallow, the Rougarou Alpha, has established an alliance with the Spawned Leader, Janusz, and the long-awaited world invasion known as the Culling is in the final planning stages. However, Gallow has a nefarious plan for revenge against the citizens of Stillwater before he enslaves the rest of the world. Meanwhile, Mad Dog travels to the White House to have his Navy Cross upgraded to the Medal of Honor. What could possibly go wrong?

While the world teeters on the precipice of a devastating war, Hunter’s degenerative condition worsens, and time is running out. Rachael leads an expedition to the Himalayas to retrieve a critical element that may lead to a cure. The stakes are higher than ever as Buford and Rue prepare for a war against the deadliest of enemies. They’ll need all the help they can get, but will it be enough?