The incidence and prevalence of cutaneous melanoma in the US and worldwide have increased over the last 5 decades. JAMA Review Author John Kirkwood, MD, discusses the epidemiology, risk factors, treatment, and prevention of melanoma with JAMA Deputy Editor Kristin Walter, MD, MS.

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• Cutaneous Melanoma

Hemorrhoidal disease, pathology of the tissue lining the anal canal, affects approximately 10 million individuals in the US. Author Jean H. Ashburn, MD, of Wake Forest University School of Medicine and JAMA Senior Editor Karen E. Lasser, MD, MPH, discuss the current evidence on the epidemiology, pathophysiology, diagnosis, and treatment of hemorrhoidal disease.

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• Hemorrhoidal Disease

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JAMA Editors' Summary

Dalbavancin, a long-acting IV lipoglycopeptide, may be an option for the treatment of complicated Staphylococcus aureus bacteremia without requiring long-term IV access. Author Thomas L. Holland, MD, MSc, from Duke University School of Medicine discusses key points of the DOTS randomized clinical trial and more with JAMA Deputy Editor Preeti Malani, MD, MSJ.

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• Dalbavancin for Treatment of Staphylococcus aureus Bacteremia
• Management of Staphylococcus aureus Bacteremia

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JAMA Editors' Summary