Icon, legend, Academy Award winning actress Regina King joins Kelly! Regina spills on THAT iconic Watch What Happens Live episode with Jackée Harry, how her late son inspired her latest venture, and if she feels his presence. She reflects on her most memorable roles (227, Boyz N The Hood, Poetic Justice, Jerry Maguire), making the transition from child actor to film actor with the vision of John Singleton, and what winning her first Oscar felt like.

Jersey Girls unite! Real Housewife of New Jersey, Teresa Giudice joins Kelly to share her thoughts on the future of the RHONJ franchise. Teresa dishes on how she met husband Luis Ruelas, how they blended their families and if he gets along with her ex-husband Joe Giudice. Teresa takes us back to the start of Real Housewives of New Jersey, how she became a cast member, and whether or not she thinks her ex-husband Joe was faithful to her. She explains why you "never go against the family" and if there's a path forward with her brother Joe Gorga and sister-in-law, Melissa Gorga.

Fresh from the Met Gala, The Better Sister star Jessica Biel joins Kelly to dish on her experience at this year's gala. Jessica shares the inspiration behind her new book, A Kid's Book About Periods, how she keeps her kids off the internet,and Kelly warns Jessica about her sons discovering Axe body spray. Plus, Kelly learns that Jessica is to blame for her recording herself eating in the shower and Jessica reveals whether or not she's husband Justin Timberlake's muse.

RHOC star Shannon Storms Beador joins Kelly to share what happened when she was recently pulled over by law enforcement officers. Shannon spills on her Love Hotel experience, the progress she’s made with dating, and Countess Luann’s opinions on Shannon’s suitors. Shannon breaks down what really happened when RHOC co-star Katie Ginella recorded her, whether or not she had any input on Alexis Bellino leaving RHOC, and where she stands with Kelly Dodd and Vicki Gunvalson. PLUS, Kelly shares a fart story that involves Justin Bieber…you don’t want to miss it!

Psychic medium Char Margolis joins Kelly live to connect callers with their deceased loved ones! Before taking callers, favorite daughter Lola Consuelos hops on to ask Char about her new music and the two bond over their soul connection. Char offers dating and health advice from the other side, and doesn’t hold back! Plus a former RHONY dials in to connect with Char.

Actresses Christina Applegate and Jamie-Lynn Sigler join Kelly to share their hall passes, growing up on camera on their shows Married With Children and Sopranos, respectively, and what it was like for Christina to be diagnosed with MS while filming Dead to Me. The actresses reflect on being bred to be “good girls," how their diagnosis affects their parenting and how they maintain hope. Christina and Jamie-Lynn dish on their Bravo obsessions, which actress’s name they use as a verb, and all about their podcast MeSsy.

Dr. Emily Morse of SEX WITH EMILY joins Kelly LIVE to take all of your pressing sex questions. Dr. Emily answers your calls about foreplay, communication, lubrication, and exploration. She advises on how open relationships work, how to get the spark back, and all those alphabet spots in the body! Plus you won’t want to miss a famous couple (Jerry O’Connell and Rebecca Romijn) call in to get some advice about their sex life!

The booking to end all bookings, Queen of EVERYTHING, Oprah graces the podcast with her presence and wisdom. After 25 years, Oprah shares the moment she knew it was time to step away from her show, and gives Kelly some career advice. She tells Kelly about the love of her life, if she ever has FOMO, coping with losing a dog, and what she really thought about her bestie Gayle King going to space. Kelly finally gets to ask Oprah if she would have liked her hostess gift...and spoiler she would REGIFT! PLUS, Oprah tells a never before shared story about her royally famous neighbors, The Sussexes (aka Harry and Meghan). And you don't want to miss hearing what Oprah's currently obsessed with and why she decided to do her new podcast, The Oprah Podcast!